四叶式三尖瓣的超声心动图与临床特征分析Echocardiographic and clinical characteristics analysis of quadrifoliate tricuspid valve
黄青霞,位晨晨,王汸,肖丽,王敏,王玲娟
摘要(Abstract):
目的:探讨四叶式三尖瓣(quadricuspid tricuspid valve, QTV)的超声心动图影像、临床表现及鉴别诊断。方法:回顾性分析我院超声心动图诊断为四叶式三尖瓣患者35例,统计并分析患者症状、体征和超声影像等资料,归纳四叶式三尖瓣的超声图像的共同特征,并由此对三尖瓣反流程度进行鉴别诊断。结果:(1)共纳入35例QTV患者,男性22例,女性13例,年龄范围35~95岁,平均年龄(74.4±13.7)岁。临床症状和体征方面,胸闷患者29例(82.9%)、心悸27例(77.1%)、乏力10例(28.6%)、腹胀6例(17.1%)、呼吸困难9例(25.7%)、下肢水肿22例(62.9%)。(2)QTV患者超声心动图表现为三尖瓣开放呈四叶“花瓣”状,收缩期三尖瓣关闭线呈“十”字征,反流束主要来自关闭线缝隙处或瓣叶交界区,所有患者反流程度均≥3+,常合并右房扩大、右室扩大、右室收缩功能减低、下腔静脉增宽和心包积液等次要特征。结论:超声心动图对QTV患者的诊断及随访具有重要价值,能够显示三尖瓣启闭的形态、是否合并其他瓣膜疾病,能够评估心腔的大小、瓣膜反流的程度及右心容量负荷,为临床用药及进一步介入或手术治疗提供重要依据。
关键词(KeyWords): 四叶式三尖瓣;反流;超声心动图
基金项目(Foundation):
作者(Author): 黄青霞,位晨晨,王汸,肖丽,王敏,王玲娟
DOI: 10.13201/j.issn.1001-1439.2026.10.008
参考文献(References):
- [1] 中国医师协会超声医师分会心脏超声专业委员会,中国医师协会心血管病分会结构性心脏病专业委员会,潘翠珍,等.三尖瓣反流介入治疗的超声心动图评价中国专家共识(2021版)[J].中华超声影像学杂志,2021,30(6):461-471.
- [2] Hahn RT,Badano LP,Bartko PE,et al.Tricuspid regurgitation:recent advances in understanding pathophysiology,severity grading and outcome[J].Eur Heart J Cardiovasc Imaging,2022,23(7):913-929.
- [3] Ho??da MK,Zhingre Sanchez JD,Bateman MG,et al.Right atrioventricular valve leaflet morphology redefined:implications for transcatheter repair procedures[J].JACC Cardiovasc Interv,2019,12(2):169-178.
- [4] Hahn RT,Weckbach LT,Noack T,et al.Proposal for a standard echocardiographic tricuspid valve nomenclature[J].JACC Cardiovasc Imaging,2021,14(7):1299-1305.
- [5] Mustafa HJ,Aghajani F,Bairmani ZA,et al.Transplacental non-steroidal anti-inflammatory drugs versus expectant management in fetal Ebstein anomaly with circular shunt:Systematic review and meta-analysis[J].Prenatal Diagn,2024,44(6-7):773-782.
- [6] 中华医学会超声医学分会超声心动图学组.中国成年人超声心动图检查测量指南[J].中华超声影像学杂志,2016,25(8):645-666.
- [7] Hahn RT,Lawlor MK,Davidson CJ,et al.Tricuspid valve academic research consortium definitions for tricuspid regurgitation and trial endpoints[J].J Am Coll Cardiol,2023,82(17):1711-1735.
- [8] Grapsa J,Praz F,Sorajja P,et al.Tricuspid regurgitation:from imaging to clinical trials to resolving the unmet need for treatment[J].JACC Cardiovasc Imaging,2024,17(1):79-95.
- [9] Davidson LJ,Tang GHL,Ho EC,et al.The tricuspid valve:a review of pathology,imaging,and current treatment options:a scientific statement from the American heart association[J].Circulation,2024,149(22):e1223-e1238.
- [10] Hungerford SL,Rye EE,Hansen PS,et al.Key echocardiographic considerations for tricuspid valve transcatheter edge-to-edge repair[J].J Am Soc Echocardiogr,2023,36(4):366-380.e1.
- [11] Wang H,Liu XT,Zheng ZL,et al.Feasibility study of applying the modified Hahn nomenclature for tricuspid valve leaflet classification in transthoracic echocardiography using the subxiphoid short-axis view[J].Echocardiography,2025,42(3):e70094.
- [12] Ramcharan TKW,Goff DA,Greenleaf CE,et al.Ebstein’s anomaly:from fetus to adult-literature review and pathway for patient care[J].Pediatr Cardiol,2022,43(7):1409-1428.
- [13] 刘奖,潘婷,赵腾月,等.三尖瓣修复技术在Ebstein’s畸形中的应用[J].临床心血管病杂志,2025,41(2):100-105.
- [14] Galeone A,Gardellini J,Perrone F,et al.Tricuspid valve repair and replacement for infective endocarditis[J].Indian J Thorac Cardiovasc Surg,2024,40(1):100-109.
- [15] Slobodov T,Marincheva G,Rahkovich M,et al.The efficacy of echocardiography-guided cardiac implantable electronic devices implantation to reduce device related tricuspid regurgitation:long-term follow-up[J].Isr Med Assoc J,2024,26(10):621-629.
- [16] Lawlor MK,Ng V,Ahmed S,et al.Baseline characteristics and clinical outcomes of a tricuspid regurgitation referral population[J].Am J Cardiol,2023,196:22-30.
- [17] Hirasawa K,Fortuni F,van Rosendael PJ,et al.Association between computed tomography-derived tricuspid annular dimensions and prognosis:insights from whole-beat computed tomography assessment[J].Eur Heart J Cardiovasc Imaging,2022,23(8):1090-1097.
- [18] Badano LP,Tomaselli M,Muraru D,et al.Advances in the assessment of patients with tricuspid regurgitation:a state-of-the-art review on the echocardiographic evaluation before and after tricuspid valve interventions[J].J Am Soc Echocardiogr,2024,37(11):1083-1102.
- [19] Khalouf A,El Shaer A,Alkhouli M.Edge-to-edge repair of a quadricuspid valve with torrential regurgitation:complementary roles of transesophageal echo,intracardiac echo,and invasive hemodynamics[J].Struct Heart,2022,6(1):100017.